AOD-9604
C$95.99
For Research Purposes Only
AOD 9604 Peptide Overview
AOD 9604 is a synthetic peptide derived from the hGH fragment, designed to exhibit anti-obesity properties through lipolysis—the breakdown of stored fat into energy components. Research indicates its potential to interact with beta-adrenergic pathways, amplifying beta(3)-AR receptor sensitivity and enhancing fat oxidation and energy expenditure without inducing IGF-1 production.
Quantity
Molecular Makeup
Molecular Makeup
- Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂
- Molecular Weight: 1815.12 g/mol
- Other Names: Tyr-hGH Fragment 177-191
Research Insights
Lipolytic Activity: Demonstrated increased beta(3)-AR expression and fat reduction in obese animal models via elevated lipolytic activity and energy expenditure.
- Obesity Trials: Clinical trials showed consistent weight loss in obese subjects over 12 weeks with no marked insulin sensitivity interruption.
- Cell Regeneration: Posited to enhance cartilage repair, stem cell differentiation, and protein synthesis vital for tissue regeneration, including bone, muscle, and cartilage.
- Cancer Research: May amplify doxorubicin efficacy in targeting breast cancer cells through improved protein binding and cytotoxicity.
AOD 9604’s therapeutic potential spans metabolic regulation, tissue repair, and oncology, supporting further scientific investigation.
Refrence
Habibullah, M. M., Mohan, S., Syed, N. K., Makeen, H. A., Jamal, Q. M. S., Alothaid, H., Bantun, F., Alhazmi, A., Hakamy, A., Kaabi, Y. A., Samlan, G., Lohani, M., Thangavel, N., & Al-Kasim, M. A. (2022). Human Growth Hormone Fragment 176-191 Peptide Enhances the Toxicity of Doxorubicin-Loaded Chitosan Nanoparticles Against MCF-7 Breast Cancer Cells. Drug design, development and therapy, 16, 1963–1974. https://doi.org/10.2147/DDDT.S367586